13 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Liver Disease - Alcohol ... DIC - Septic shock ... catastrophes, Acute ... comparison #diagnosis #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... Hepatic Artery: Shock ... - Sophia Hayes MD ... #hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
kidney disease, Acute ... patients), "Hospital-acquired ... independent of alcohol ... differential #diagnosis #causes ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... transformation to acute ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Infection exposure (l MD ... for HIV, HCV - Alcohol ... evaluation: not required ... or if a primary hematologic ... #Workup #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
treatments Search ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... - Acute Bleeding ... by a hemophilia treatment ... Avoid meds that ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... dysfunction (16%) • Shock ... Treat primary cause ... #treatment #management ... #hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... endocarditis, sepsis, shock ... persist → DIC, MODS ... Canimorsus #Skin #Rash #dermatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... : - Acute kidney ... HCV, DILI, HCC, acute ... Multiorgan failure or shock