22 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Liver Disease - Alcohol ... DIC - Septic shock ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Failure (ACLF) Clinical ... months without treatment ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
->treatments include ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute ... Hypoglycemia - Alcohol
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... exclude other causes ... : - Acute kidney ... Multiorgan failure or shock
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Lutzomyia verrucarum Clinical ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... organ damage Clinical ... dysfunction (16%) • Shock ... #treatment #management ... #hematology
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
GrepMed Handbook Clinical ... on ABx) → Acute ... Toxic Megacolon, Shock ... can be community-acquired ... Ileus, Megacolon, Shock
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... pneumonia • Chronic alcoholism ... Lung Abscess - Clinical ... #differential #causes ... #management #treatment
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... At least 3 of (Acute ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Purtilo (XLP) Acquired ... Treatment: • ... Lymphohistiocytosis #diagnosis #management ... #rheumatology