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diagnosis management microbiology differential pharmacology syndrome idsa neurology opportunistic activetb american chagas classification cns criteria disease encephalopathy endocarditis hematology hivaids
Bacteremia Quick Reference - Treatment Duration Gram Negative Bacteremia: • Avoid: Aminoglycosides and tigecycline • Catheters should
Reference - Treatment ... removed in septic shock ... follow up cultures required ... of metastatic infection ... #Duration #infectiousdiseases
Adjuvant therapies in critical care: steroids to treat infectious diseases - Severe Community Acquired Pneumonia
steroids to treat infectious ... Severe Community Acquired ... severe community-acquired ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Management #Treatment
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Bug: Atypical bacteria ... Aggressive: MRSA bacteremia ... Immunocompromise Treatment ... • Secondary to Treatment ... diff) • Hospital-Acquired
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Toxic Megacolon, Shock ... Epidemiology: • #1 ... can be community-acquired ... 10 mg/kg IV x 1 ... #infectiousdiseases
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Overview Normal: < 1% ... predictive of a serious infection ... overlook severe infections ... culture proven bacteremia ... hypotension or septic shock
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Purtilo (XLP) Acquired ... CMV, HHV8,...), Bacteria ... Unknown cause Treatment ... diagnosis #management #treatment
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
vs non-infectious ... Septic Shock • ... recognition & treatment ... (within 1 hour) ... #sepsis #sirs #shock
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock ... necrosis STSS Treatment ... IVIG 1g/kg on day 1, ... day 2 + 3 BIDMC Infectious ... Syndrome #STSS #treatment
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
intracellular rod-shaped bacteria ... Pathophysiology: 1. ... Tuberculosis: 1. ... lung disease, bacteremia ... Tuberculosis Treatment
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
common route of infection ... Incubation is 1 ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #infectiousdiseases
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