12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Positive ANA ≠ Autoimmune ... context of other symptoms ... ANA #patterns #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
, autoimmune hepatitis ... Anti-CCP, Rheumatoid ... microsomal) - Autoimmune ... diagnosis #table #rheumatology ... #antibodies
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
accompanies other autoimmune ... diseases like rheumatoid ... erythematosus (SLE ... ) Signs / Symptoms ... #Symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... , holster sign, ... Can also see mechanics ... Myositis #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... constitutional symptoms ... Rheumatologic Disease ... arthritis • SLE ... Symmetrical: • RA • SLE
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Auto-Antibodies ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is an autoimmune ... Sjogren syndrome, rheumatoid ... arthritis, SLE ... test - Cogan sign ... - Peek sign
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis, rheumatoid ... disease • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis: Systemic rheumatic ... Presentation - Systemic Symptoms ... purpura: strong sign ... C-ANCA) pattern: antibodies ... vasculitis, and SLE
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology