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differential management classification disorders hematology myositis neurology scleroderma vasculitis ana antibodies antinuclear autoantibodies cord erythematosus fungal hemeonc hemophagocytic hlh infections
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... autoimmune disease ... and Symptoms: ... #SSc #rheumatology ... #diagnosis #signs
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... @AnnKumfer #Systemic ... #Sclerosis #Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... Thyroid, Autoimmune ... ANA #patterns #rheumatology ... #diagnosis #differential
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... weakness, less systemic ... symptoms, and less ... , holster sign, ... #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
(MS) is an autoimmune-mediated ... central nervous system ... Diagnosis - Based ... Signs and symptoms ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... with lymphatic system ... Classic - Nodular Sclerosis ... pattern of spread, B symptoms
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential Diagnosis ... and signs below ... , Scleroderma, Systemic ... sclerosis - MCTD ... differential #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... #rheumatology #
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... • Sclerosing mediastinitis ... acute pulmonary, systemic ... the circulatory system ... fever • Septic shock
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