18 results
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Systemic Sclerosis ... (Scleroderma) ... @AnnKumfer #Systemic ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... sclerosis/scleroderma ... sclerosis/scleroderma ... ANA #patterns #rheumatology ... #diagnosis #differential
Scleroderma Mimics
 • Scleredema
 • Scleromyxedema (papular mucinosis)
 • Eosinophilic Fasciitis
 • Nephrogenic Systemic Fibrosis
 •
Scleredema ... • Nephrogenic Systemic ... Fibrosis • POEMS Syndrome ... #Mimics #rheumatology ... #differential #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE • Scleroderma ... growth (e.g.. shock ... • Nephrotic syndrome ... #Secondary #dermatology ... #Differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... , holster sign, ... anti-synthetase syndrome ... Myositis #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Neurologic system ... Telangiectasia • Scleroderma ... Thickened skin • Scleroderma ... #joint #pain #differential ... #diagnosis #rheumatology