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lupus management pathophysiology erythematosus systemic allergy anaphylaxis arteritis behcet comparison coronavirus covid19 differential disease endocarditis extrapulmonary gastrointestinal gca giantcell infective
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... #MSK #Musculoskeletal ... #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Erythematosus #SLE ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
Extrapulmonary manifestations ... of COVID-19 • Neurologic ... arrhythmias, Cardiogenic shock ... Extrapulmonary #Diagnosis ... #Signs #Symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... pain • Extra-CNS complications ... #Optica #NMO #Manifestations ... #diagnosis #neurology ... #symptoms #signs
Manifestations of Anaphylaxis by Body System Dermatologic/mucosal - Eyes: periorbital swelling/erythema, injected conjunctiva, tears - Oral mucosa:
: bradycardia, shock ... abdominal cramps Neurologic ... cessation of play #Diagnosis ... #Allergy #Signs ... #Symptoms #Anaphylaxis
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 Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... is required for diagnosis ... conditions: Autoimmune (SLE ... #table
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
M > F Clinical Manifestations ... skin injury) • Neurologic ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... and ophthalmic complications ... Manifestations depend ... systemic sx + signs ... #Symptoms #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Evaluate for NMO, SLE ... Disorders: - SLE ... #management #neurology
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