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Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential Diagnosis ... Algorithm - Diabetes ... Insipidus Workup ... #Sodium #nephrology ... #insipidus #DI
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
- Differential Diagnosis ... Insensible losses Sodium ... Insipidus (Decr ... Insipidus (Incr ... #Table #Causes
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
- Differential Diagnosis ... Algorithm Hypernatremia ... water loss, Serum Sodium ... 300 mmol/kg • Diabetes ... Insipidus Hypodipsia
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... • Euvolemic: Diabetes ... insipidus (central ... #nephrology #sodium
Diabetes Insipidus - Diagnosis Algorithm
Tests:
 • Osmolality, Urine AND/OR
 • Osmolality, Serum or Plasma AND
 •
Diabetes Insipidus ... - Diagnosis Algorithm ... Plasma AND • Sodium ... #Insipidus #Diagnosis ... #Algorithm #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
of epithelial sodium ... ATPase Nephrogenic diabetes ... insipidus - Vasopressin ... Kidney #Nephrology #Diagnosis ... #Differential #Table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... • Nephrogenic diabetes ... insipidus • Kidney ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
simply a clinical diagnosis ... #algorithm #management ... cardiology #treatment #table ... #heartfailure #chf ... icu #clinical #pharmacology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
disease b) CHF ... event, follow ACC algorithm ... Stable patients ... Diabetes regimen ... stratification #diagnosis