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differential management erythematosus lupus oncology systemic anemia autoimmune classification disease leukemia myositis thrombocytopenia vasculitis workup agglutinin antinuclear apml arterial autoantibodies
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... Signs and Symptoms ... of Hemolytic Anemia ... #hematology #diagnosis ... #signs #symptoms
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... Diagnosis: • hemolytic ... #anemia #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Auto-Antibodies ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... ) CLL Symptoms: ... Lymphoma (SLL) ... #Leukemia #Hematology ... #Oncology #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... ), Sjogren's Syndrome ... , Sjögren Syndrome ... #rheumatology #diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... anti-synthetase syndrome ... arthritis (19% ... Can also see mechanics ... #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... workup #oncology #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
cutaneous lupus • Arthritis ... pericarditis • Hematologic ... Highly specific antibodies ... Erythematosus #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis ... #Rheumatology
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