16 results
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... Signs/Symptoms ... #Lupus #Erythematosus ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(RA) or systemic ... lupus erythematosus ... (SLE) Signs / ... #Pathophysiology ... #Diagnosis #Signs
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
gangrenosum • IBD • RA ... lesions • Discoid lupus ... #dermatology ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... (SLE), Systemic ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... #SLE #systemic ... #erythematosus # ... signs #symptoms ... #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- (Reiter’s syndrome ... autoimmune disease ... Lupus - with Systemic ... Lupus Erythematosus ... other symptoms
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Atypical HUS, autoimmune ... (RA, Sjogren's) ... antiphospholipid syndrome ... Lupus Erythematosus ... #differential #hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... (RA), Systemic ... lupus erythematosus ... (SLE), Sarcoidosis ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... : • Symptoms limited ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - Arthritis ... #Systemic #Lupus ... #signs #symptoms ... #differential #rheumatology