16 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Differential Diagnosis ... 1000): • DILI (Drug-induced ... liver injury) ... • Ischemic Hepatopathy ... Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... #differential # ... gastroenterology #algorithm
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Injury - Ichemic ... obstruction - Drug-Induced ... liver injury ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Diagnosis Algorithm ... /Toxins • Ischemia ... • Others #LFTs ... Diagnosis #Algorithm
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... disease, Hepatic ischaemia ... Hepatic vascular disorder ... #Injury #Diagnosis ... #Algorithm #hepatology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... history (cardiac, liver ... renal disease), drug ... #EM #IM #Nephro ... #Algorithm #Ddxof
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... , Viral, Ischemia ... #diagnosis #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Congenital - Rare • Drugs ... Iatrogenic) • Liver ... #Diagnosis #Algorithm ... #Causes #Hematology