12 results
Hepatitis B Management in Cancer

DOI: 10.1200/JCO.20.01757

#HepatitisB #HBV #HepBV #Management #Cancer #oncology #hepatology #algorithm
Hepatitis B Management ... JCO.20.01757 #HepatitisB ... #HBV #HepBV #Management ... #Cancer #oncology ... #hepatology #algorithm
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... serologic evidence of hepatitis ... Chronic Hepatitis ... #HepatitisB #HBV ... Management #Treatment #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... disease, Hepatic ischaemia ... hepatitis fibrosis ... • Autoimmune hepatitis ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Hepatitis > ... - Acute Viral Hepatitis ... , Toxic Hepatitis ... 5-10x normal - Chronic ... #hepatology #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
, HBV, HCV, HEV, ... EBV, HSV, CMV, ... Autoimmune: Autoimmune hepatitis ... viral hepatitis ... #hepatitis #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... CMV, HSV, VZV ... • Vascular: Ischemic ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• CMV • HIV ... Tuberculosis • Hepatitis ... Age > 50 • Chronic ... #Causes #Hematology ... #Oncology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... , CMV, HSV • Toxic ... NAFLD, Autoimmune hepatitis ... Pregnancy, Alcoholic Hepatitis ... Sepsis, Viral Hepatitis
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... diseases including HBV ... HCV, DILI, HCC, ... HIV, TB - Multiorgan ... #Alcoholic #Hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Check Acute viral hepatitis ... serologies, HCV ... Check Acute viral hepatitis ... serologies, HCV ... viral hepatitis