6 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... disorder (e.g. ascites ... ), Chronic hepatitis ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
normal - Infection (EBV ... /CMV), Alcoholic ... 5-10x normal - Chronic ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Cirrhosis - Alcoholic ... hepatitis ... peritonitis - HIV-associated ... Mediterranean fever - Vasculitis ... #differential #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... > 2 • NASH, Chronic ... #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... blood, urine and ascites ... #Hepatitis #Management ... #Algorithm #hepatology