8 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
, HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 20x normal - Acute ... normal - Infection (EBV ... /CMV), Alcoholic ... #hepatology #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... • Iatrogenic: DILI ... ALT Ratios: • Alcoholic ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... Sophia_Hayes_MD #Liver #Injury ... #algorithm #hepatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Acute Kidney Injury ... (AKI) - Acute increase ... cell casts) • Ischemia ... #Acute #KidneyInjury
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... kidney injury with ... diseases including HBV ... HCV, DILI, HCC, ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... serologies, HCV ... viral hepatitis ... ALT Ratios: • Alcoholic ... #differential #Hepatology