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diagnosis differential causes lfts management transaminitis nephrology aclf chemistry chronic cirrhosis dehydrogenase dili druginduced elevated failure gastroenterology hepatitisb hepatocellular indications
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... 20x normal - Acute ... normal - Infection (EBV ... #Injury #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... Hepatic ischaemia ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... #injury #hepatitis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #Injury #Differential ... #algorithm #hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... severe liver injury ... liver failure ... #HepatitisB #HepBV ... Indications #management #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Circulation Failure Kidney ... Failure Infections Alcohol-Associated ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... serologies, HCV ... viral hepatitis ... ALT Ratios: • Alcoholic ... #differential #Hepatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Acute Kidney Injury ... (AKI) - Acute increase ... cell casts) • Ischemia ... • Drugs • HIV
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... cryoglobulins, hepatitis ... #Kidney #Injury ... #AKI #Workup #Algorithm
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