13 results
diagnosis differential injury transaminitis causes acute dili abnormal aclf ah aih autoimmune chronic cirrhosis criteria druginduced elevated failure function hepatocellular
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... AST:ALT > 2.5 - Alcoholic ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... /Toxins • Ischemia ... hepatitis • Drugs ... • Others #LFTs ... #Hepatology #LiverEnzymes
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Chronic Viral Hepatitis ... 1000): • DILI (Drug-induced ... • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
valproate, azoles), Drugs ... (MDMA), Alcohol ... • Vascular: Ischemic ... #algorithm #Transaminitis ... #LFTs #hepatitis
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
factors • Possible ischemic ... ) or metabolic liver ... liver disease ( ... suspect drug within ... #hepatology #criteria
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... #algorithm #gastroenterology ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... Drug-Induced Liver ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... 15X ULN - Drugs ... , Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... HEV, EBV, CMV), Alcohol-related ... Hepatic ischaemia ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Hepatitis • Drug ... #Causes #Hepatology
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