23 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... AST:ALT > 2.5 - Alcoholic ... #Patterns #Liver ... #Injury #hepatology ... transaminitis #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... Others #LFTs #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Drugs, Viral, Ischemia ... #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic #differential ... #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... Disease • Alcohol ... Macrocytic #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... HSV • Toxic: Alcohol ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure Infections Alcohol-Associated ... Hepatitis Procedures Management ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Alcoholic Hepatitis - Management Algorithm
1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Diagnosis Algorithm ... MRCP, ERCP, liver ... #Diagnosis #Algorithm ... #gastroenterology ... #hepatology