18 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Infection (EBV/CMV ... ), Alcoholic cirrhosis ... 5-10x normal - Chronic ... #Injury #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... , Alcohol-related ... Hepatic ischaemia ... ), Chronic hepatitis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... E, B, D, EBV, CMV ... HSV • Toxic: Alcohol ... #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... #Causes #Hematology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Trauma: Shock liver ... • Autoimmune hepatitis ... See Updated Schema ... Differential #Diagnosis #causes ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Inflammatory • Alcoholic ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Non-megaloblastic: Alcohol ... use, Liver disease ... independent of alcohol ... differential #diagnosis #causes ... #hematology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Sarcoidosis Toxic - Alcohol ... Nonalcoholic fatty liver ... heart failure (chronic ... #Differential #Hepatology ... #Cirrhosis #Causes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
/B/C/D/E, EBV, CMV ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis