14 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Infections Macrocytic ... Non-megaloblastic: Liver ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypoproliferative Macrocytic ... Anemia • 812 ... Hypothyroid • Liver ... #diagnosis #algorithm ... #hematology #workup
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
- "Microcytic" ... kidney disease, Acute ... - "Macrocytic" ... : Alcohol use, Liver ... diagnosis #causes #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... 100-500): • NAFLD ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (cell) volume (MCV ... 95 (or 100) is macrocytic ... High in acute blood ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... • Drugs Oval Macrocytes ... Disease #Macrocytic ... #Causes #Hematology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... Infection (EBV/CMV ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... ALT < 5x ULN • NAFLD ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Polychromatic Macrocytes ... Normal RBCs • Acute ... #Causes #Hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... antitrypsin • Other: NAFLD ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis