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differential transaminitis abnormal causes dili hepatitis tests acute drug druginduced elevated elevation enzymes functiontest gastroenterology idiosyncratic induced interpretation laboratory liverenzymes
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... 100-500): • NAFLD ... injury) • Ischemic ... #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... : Liver Injury ... Liver Injury Differential ... #Liver #Injury ... #hepatology #algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Hepatocellular ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... injury >2 ... Transaminitis #diagnosis ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Antitrypsin • Other: NAFLD ... #Acute #algorithm ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value • Hepatocellular ... gastroenterology #algorithm ... gastroenterology #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... intrahepatic cholestasis, hepatocellular ... injury, genetic ... Interpretation #diagnosis ... #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... non-alcoholic fatty ... #LFTs #Abnormal ... #Algorithm #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... alternative causes • Hepatocellular ... disease, Hepatic ischaemia ... #Injury #Diagnosis ... #Algorithm #hepatology
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