17 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... #treatment #hematology
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm
Congenital Anomaly / Disorder:
 •
Causes of Sudden ... Accidental* Other: • Acute ... Sudden Infant Death Syndrome ... 80% of SUDI • Risk ... #Causes #Peds #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Definition: acute ... ischemic disorder ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis #Algorithm
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... by case) • Surgery ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... limb ischemia, ... TLS #diagnosis #management ... #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... severity Treatment - Acute ... Avoid meds that ... ↑ bleeding risk ... #treatment #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Acquired Risk ... • Nephrotic Syndrome ... , Ischemic Liver ... cardiovascular risk ... pathophysiology #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology