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diagnosis treatment differential oncology disease pediatrics erythematosus infant leukemia lupus neurology sle systemic timeline aion all anteriorischemicopticneuropathy apml arterial autoimmune
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Risks: infection ... transformation to acute ... #treatment #hematology
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Causes of Sudden ... Accidental* Other: • Acute ... Sudden Infant Death Syndrome ... 80% of SUDI • Risk ... #Causes #Peds #
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Treatment Schema ... for Standard-Risk ... Consolidation & CNS ... oncology #pediatrics #peds ... #management
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Anterior ischemic ... Definition: acute ... ischemic disorder ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis #Algorithm
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... by case) • Surgery ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... limb ischemia, ... TLS #diagnosis #management ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... retinal tears, Ischemia ... #diagnosis #management ... signs #symptoms #rheumatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... severity Treatment - Acute ... Avoid meds that ... ↑ bleeding risk ... #treatment #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... • Nephrotic Syndrome ... , Ischemic Liver ... coagulation and other causes ... pathophysiology #hematology
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