21 results
diagnosis differential treatment oncology disease classification mds myelodysplastic neurology vasculitis apml arterial autoimmune behcet behcets capillary cerebritis clarksons cns cvid
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... • Risks: infection ... Myelodysplastic #Syndrome ... #treatment #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... by case) • Surgery ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Acquired Risk ... • Nephrotic Syndrome ... , Ischemic Liver ... coagulation and other causes ... pathophysiology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
increased infection risk ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... AKI, acute limb ischemia ... TLS #diagnosis #management ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... Avoid meds that ... ↑ bleeding risk ... #treatment #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... of age • Most common ... retinal tears, Ischemia ... #diagnosis #management ... signs #symptoms #rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... circulation = risk ... Better call hematology ... workup, think about common ... #workup #hematology
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