35 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... 5-10x normal - Chronic ... #Injury #hepatology ... #differential #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... Cirrhosis • Chronic ... injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
Chronic Diarrhea - Differential Diagnosis Algorithm
Steatorrhea
 - Maldigestive
    • Pancreatic Insufficiency
 - Primary
Algorithm Steatorrhea ... Overgrowth • Liver ... • Mesenteric Ischemia ... CoIits • Ischemic ... #Algorithm
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Mesenteric Ischemia ... Schema Chronic: ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #Diagnosis #algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Injury (DILI) ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #Algorithm #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... vein: Budd-chiari syndrome ... #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #differential #Diagnosis ... gastroenterology #algorithm ... gastroenterology #hepatology