7 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of ... Tumor Lysis Syndrome ... (TLS) and Treatment ... #TLS #diagnosis ... #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Initial workup ... of the above Treatment ... #diagnosis #management ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
AKI, acute limb ischemia ... organ damage • Treatment ... leukapheresis - TLS ... values: Elevated K, ... #TLS #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis (TLS ... /crush injury, ischemia ... reabsorption) Workup ... ileus/obstruction (ischemia ... #potassium #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #Diagnosis ... #Classification ... #Nephrology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... antibiotics TLS ... changes: high K, ... low Ca - q8 h TLS ... #HemeOnc #Diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... HIV, Influenza, TSS ... perfusion → renal ischemia ... #Differential #Diagnosis ... #nephrology