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diagnosis hepatology cardiology causes lfts neurology rheumatology syndrome algorithm checklist chf cirrhosis endocarditis heartfailure hepatitis indications infectiousdiseases nephrology renal signs
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Hepatopathy • Acute ... injury) • Ischemic ... #Diagnosis #hepatology ... #transaminitis
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... injury - Viral ... #Causes #Differential ... #Hepatology #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury → liver ... Injury Differential ... • Vascular: Ischemic ... #Injury #Differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... months without treatment ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Mixed - Check Acute ... injury < 26 weeks ... muscle injury: ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ascites removed • Acute ... kidney injury ( ... #Cirrhosis #treatment ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
subclinical disease to acute ... liver failure ... injury, though ... regarding need for treatment ... #Hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Lumbar Puncture, EEG ... Treatment: ... cerebritis #diagnosis #management ... #treatment
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