58 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... #Differential # ... Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... gastric bypass), LFT ... (liver disease) ... #Differential # ... Causes #Workup #hematology
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
RA Rheumatic disorders ... • Inflammatory disorders ... of Liver & Lung ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Probable bone marrow disorder ... - TSH, LFTs, ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Neutrophils - Differential ... Solid Tumour (e.g ... • Metabolic disorders ... Myeloproliferative Disorder ... Algorithm #Causes #Hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury Differential ... • Vascular: Ischemic ... #Diagnosis #hepatology ... Transaminitis #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Differential #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology