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diagnosis management syndrome joint pain vasculitis classification dermatology erythematosus lupus msk signs sle symptoms systemic treatment workup activation adultonset ana
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
• Mechanism: ischemic ... Osteomyelitis / Septic Arthritis ... #Joint #Pain #SickleCell ... #Disease #differential ... diagnosis #causes #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
polychondritis, GPA • Ischemic ... IBD, Whipple's disease ... , Vasculitis (e.g ... #joint #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... necrosis, and Paget disease ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Fever, Arthralgia/arthritis ... fraction < 20% Differential ... management #treatment #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... ) Differential Diagnosis ... retinal tears, Ischemia ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... that will cause ischemia ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... Noncontiguous spread • Clinical ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology ... #diagnosis #differential
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Group for Behget's Disease ... ulcers - Ocular disease ... test Most Common Clinical ... vasculitis) • Arthritis ... Diagnosis #criteria #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... idiopathic arthritis ... Diagnosis #Management #Hematology ... #Rheumatology
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