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diagnosis hematology differential hypercoagulable management neurology anticoagulation antiphospholipid arterial breakthrough cardiology cerebritis checklist cns cryofibrinogenemia dvt embolism endocarditis erythematosus evaluation
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Behcet's disease - APLS ... - May-Thurner syndrome ... Recurrent #DVT #VTE ... anticoagulation #hematology ... #differential #algorithm
How do you work up an ischemic CVA? A) Initial Evaluation • ABCs • IV access, monitor
How do you work ... up an ischemic CVA ... ) B) Evaluate ischemic ... udaygulati #ischemic ... #CVA #stroke #workup
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
- No other workup ... - Strong Medicine ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... prevention (statin for CVA
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... , Ischemic Liver ... coagulation and other causes ... pathophysiology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... Hypercoagulable Workup ... maternal chromosomal causes ... #hematology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
to perform own ADLs ... history of: a) Ischemic ... event, follow ACC algorithm ... • <6mo since stroke ... • <3mo since VTE
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS ... Cholesterol emboli syndrome ... Septic emboli cause ... Early embolic/ischemic ... Treat underlying cause
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