40 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #Injury #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... • NAFLD • Cirrhosis ... injury) • Ischemic ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... Infiltrative • Cirrhosis ... • Others #LFTs
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Ichemic hepatitis ... hepatitis - Wilson disease ... #Differential #Hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Renal Disease, Liver ... Reticulocytosis • Liver ... Diagnosis #Algorithm #Causes ... #Hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pancreatic Disease ... Disease #Macrocytic ... Diagnosis #Algorithm #Causes ... #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
pylori test (GI symptoms ... changes), high MCV anemia ... gastric bypass), LFT ... (liver disease) ... #Workup #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
chronic kidney disease ... : Alcohol use, Liver ... disease (independent ... differential #diagnosis #causes ... #hematology