13 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #hepatology #LFTs ... #differential #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... - Differential Diagnosis ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #hepatology #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... or symptoms of ... #differential #Diagnosis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... Differential Diagnosis ... • Vascular: Ischemic ... #hepatology #algorithm ... Transaminitis #LFTs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... causes direct injury ... - Myocardial ischemia ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... : • Triad of symptoms ... urine • Other symptoms ... perfusion → renal ischemia
Differentiating type-I vs. type-II MI

Sorting this out is difficult, often relying heavily on clinical judgement.

A key
relying heavily on clinical ... of myocardial ischemia ... If the same symptoms ... #Diagnosis #Myocardial ... Definition #NSTEMI #Comparison
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Necrosis Etiology: - Ischemia ... restored to esophagus Clinical ... melena - Other GI symptoms ... retrosternal chest pain Diagnosis ... #management #gastroenterology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Digital ischemia ... quantify renal injury ... pericardial effusion) • PFTs ... or serologies + symptoms ... #differential #diagnosis
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... - Atypical Clinical ... , facial nerve ischemia ... Imaging (if atypical symptoms ... prevent corneal injury