21 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... that will cause ischemia ... Lumbar Puncture, EEG ... cyclophosphamide • Ischemic ... Erythematosus #SLE #CNS #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... AKI, acute limb ischemia ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... #Differential #Diagnosis
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
syndrome, ARVC) ... • Myocardial ischemia ... • Underlying ischemic ... Digoxin toxicity Symptoms ... 300 = NSVT EKG
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
diarrhoea, Short bowel syndrome ... Hypercholesterolaemia, Ischaemic ... , Neutropenia, Thrombocytopenia ... Copper #Deficiency #diagnosis ... #riskfactors #symptoms
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... TTP = thrombotic thrombocytopenic ... , extremities (ischemia ... proteinuria #nephrotic #syndrome ... #nephrology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... • Nephrotic Syndrome ... , Ischemic Liver ... Heparin-induced thrombocytopenia ... #differential #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... retinal tears, Ischemia ... #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... : >3 symptoms, or ... #management #hematology ... #oncology