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differential causes rheumatology liver management transaminitis anemia cardiology hepatitis injury treatment abdominal classification disorders macrocytic neurology pain pulmonary thrombocytopenia thrombocytosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
Mesenteric Ischemia ... GPA, IgA, MPA) Acute ... inflammation (e.g ... #Mesenteric #Ischemia ... #Diagnosis #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... - Differential Diagnosis ... Hepatopathy • Acute ... liver injury) • Ischemic ... #hepatology #transaminitis
Approach to Diarrhea - Differential Diagnosis and Workup Algorithm Acute Diarrhea (MINT): • Medications • Infections: Inflammatory
- Differential Diagnosis ... and Workup Algorithm ... Acute Diarrhea ... Necrosis • Toxic (e.g ... radiation, ingestions ischemia
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
- Differential Diagnosis ... Algorithm Severe ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
Diffuse Acute Abdominal ... Algorithm Look ... • Mesenteric ischemia ... Metabolic disease (e.g ... Irritable bowel syndrome
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... for workup, including ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Constant Pain (Ischemia ... ) - Acute Onset ... Septic Embolism (e.g ... Fat Embolism (e.g ... Mycotic Aneurysm (e.g
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Algorithm for Transaminitis ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
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