18 results
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Drugs/Toxins • Ischemia ... • Drugs • AIH ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Differential Diagnosis Algorithm ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... Transaminitis #Algorithm ... #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
, HSV, VZV • Medications ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... that will cause ischemia ... cyclophosphamide • Ischemic ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Compartment Syndrome, Medications ... Other • ATN: Ischemia ... Pigment, Protein) • AIN ... Differential #Diagnosis #nephrology ... #causes #algorithm
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
peripheral tracking of air ... i.e. mesenteric ischemia ... finding is an urgent indication ... venousgas #ultrasound #hepatology ... pocus #clinical #air
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... gastroenterology #algorithm ... gastroenterology #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
factors - Possible ischemic ... metabolic liver disease ... (Wilson disease ... Hepatitis #Diagnosis #Hepatology ... #AIH
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Alcoholic Hepatitis (AH ... factors • Possible ischemic ... metabolic liver disease ... (Wilson disease ... #hepatology #criteria
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... duration), Several medications ... Alcohol-related liver disease ... , Hepatic ischaemia ... #hepatology