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diagnosis anticoagulation differential doac oral rheumatology thrombosis treatment algorithm arterial bileduct biliary bridging cardiology cerebritis cns cryofibrinogenemia dilatation dilated direct
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct ... #Oral #AntiCoagulant
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
procedure Stop anticoagulant ... #Reversal #NOAC ... #Oral #anticoagulant ... #hematology #management ... #pharmacology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... Pathway - Aspirin, anticoagulants
Anticoagulant Bridging • Switching from LMWH • Switching from UFH • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... Kfischer_10 #Anticoagulant ... anticoagulation #pharmacology ... #management #hematology
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... sludge), Mirizzi's syndrome ... Parasitic infection, Ischaemic ... Biliary #Dilatation #causes ... differential #diagnosis #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... AKI, acute limb ischemia ... TLS #diagnosis #management ... #hematology
Anticoagulant Therapy after PCI (patients with AFib) Dual-Therapy Preferred: • Triple therapy = increased bleeding
Anticoagulant Therapy ... risk outweighed ischemic ... due to use of DOAC ... anticoagulation #PCI #pharmacology ... #management #cardiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
• Nephrotic Syndrome ... , Ischemic Liver ... considered in all cases ... coagulation and other causes ... pathophysiology #hematology
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
If concern for ischemic ... - Cirrhosis: case-by-cased ... PVT #Treatment #management ... #Algorithm #hepatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
limb and bowel ischemia ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
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