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diagnosis management erythematosus sle systemic table druginduced summary ana antinuclear associations comparison dil polychondritis relapsing
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... LAC) • Sjogren Syndrome ... #Rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... months) and of autoantibodies ... evocative of SLE versus ... Workup: - ANA ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... evocative of SLE versus ... Workup: - ANA ... life-threatening • Treatment ... Management #Summary #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... SLE-SSc-AlM overlap syndromes ... #Antinuclear #autoantibodies ... erythematosus #diagnosis #rheumatology ... #table #ANA
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
laboratory findings (ANA ... • Anti-Ro/SSA autoantibodies ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... antibodies • (-) ANA
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Workup: - ANA ... constitutional symptoms • Treatment ... months) and of autoantibodies ... #DIL #rheumatology ... #diagnosis #treatment
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
• MAGIC syndrome ... • Vexus syndrome ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment ... Polychondritis #rheumatology
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