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lfts dili elevated abnormal acute causes chemistry cholestatic dehydrogenase drug druginduced enzymes function induced interpretation laboratory lactate ldh liverfunctiontests management
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Calculate R-Value • Hepatocellular ... #Injury #Idiosyncratic ... #differential # ... #algorithm #gastroenterology ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... Injury - Differential ... Liver Injury Differential ... #Differential #Diagnosis ... #hepatology #algorithm
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Injury Hepatocellular ... Liver Injury ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... Pattern #LFTs #transaminits ... obgyn #obstetrics #hepatology ... #diagnosis #differential ... #algorithm
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Diagnosis Framework ... injury) • Ischemic ... #Diagnosis #hepatology ... #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Acute #algorithm ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALP) • R > 5: Hepatocellular ... Check Acute viral hepatitis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... #injury #hepatitis ... diagnosis #algorithm ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Hepatocellular ... #Algorithm #diagnosis
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