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diagnosis liver differential algorithm interpretation management transaminitis acute bismuth calling chemistry cholangitis cirrhosis classification congenital consultation dili drug elevation function
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... (GGT) - Liver, biliary ... hepatocellular injury ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... the liver ALP - Biliary ... Hepatocellular injury ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
hemolysis or liver injury ... breastfeeding jaundice ... and breastmilk jaundice ... #hepatology #diagnosis ... #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
dose dependent injury ... Chronic - ongoing ↑ LFTs ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Extrahepatic - Biliary ... - Obstruction: Biliary ... • Bilirubin - ... week • Direct bilirubin ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... • Bilirubin - ... week • Direct bilirubin ... #differential #Hepatology ... transaminitis #LFTs
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Important findings: jaundice ... - Vitals - LFTs ... Calling #Referral #Hepatology ... #Gastroenterology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... hyperpigmentation • Jaundice ... slightly elevated • Bilirubin ... No extrahepatic biliary ... diagnosis #workup #hepatology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook Presentation: • Epigastric abdominal pain (90%, characteristically
90%) • Other: Jaundice ... Lipase, Ca2+, LFTs ... • Imaging: US (biliary ... MRCP (necrosis, biliary ... Management #Treatment #Gastroenterology
Classification for benign biliary strictures Bismuth classification I - Low CHD stricture, > 2 cm distal to hilum II
Classification for benign biliary ... A - Small duct injury ... system D - Injury ... strictures #diagnosis #hepatology ... #gastroenterology
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