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diagnosis hepatology differential algorithm causes syndrome transaminitis abnormal ascites gastroenterology injury interpretation management pbc physicalexam primary acute albumin calling chemistry
Clinical Examination for Liver and Biliary Diseases 1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Examination for Liver ... and Biliary Diseases ... Xanthelasma and jaundiced ... #physicalexam #cirrhosis ... #liver #disease
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Important findings: jaundice ... Gl History - Cirrhosis ... - Vitals - LFTs ... MELD - Chronic liver ... US - Prior liver
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... , biliary epithelium ... , NOT in bone Total ... Conjugated/DBili) - Biliary ... Function #Tests #LFTs
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... discomfort Signs: Jaundice ... Liver biopsy findings ... #PBC #Primary #Biliary
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... , Portal Vein Thrombosis ... #Patterns #Liver ... Injury #hepatology #LFTs
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Clues to non-cirrhotic ... Intrahepatic: • Cirrhosis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... pregnancy • Primary biliary
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... /Liver failure ... hyperpigmentation • Jaundice ... or higher • Liver
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... disease US — Normal ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... AST): • US - Normal ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... Burak @kwburak #LFTs
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Diagnosis Algorithm Portal ... Prehepatic: • Portal ... - Hepatic: • Cirrhosis ... disease • Acute liver ... failure • Primary biliary
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