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diagnosis pediatrics differential algorithm hepatology management neonatal bhutani gastroenterology nomogram risk stratification thresholds unconjugated bilirubin bilirubinemia causes congenital ddxof indirect
Algorithm and Differential Diagnosis of Hyperbilirubinemia Direct = Conjugated Indirect = Unconjugated #Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Direct = Conjugated ... Indirect = Unconjugated ... #Diagnosis #Jaundice ... #Hyperbilirubinemia ... #Indirect #Conjugated
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Management #EM #IM #GI #Jaundice ... #Hyperbilirubinemia ... Differential #Algorithm #Direct ... #Indirect #Conjugated
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Unconjugated hyperbilirubinemia ... (predominantly indirect ... hyperbilirubinemia ... (predominantly direct
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... the blood • Defect ... predominantly a mixed conjugated
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Hyperbilirubinemia ... II) Hepatic - Conjugated ... Hyperbilirubinemia ... Cholangitis #Jaundice
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Approach to Conjugated ... Hyperbilirubinemia ... elevation + >20% conjugated ... #Hyperbilirubinemia ... #direct #bilirubin
Approach to Neonatal Jaundice Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... of pathologic hyperbilirubinemia ... #Diagnosis #Peds ... Pediatrics #Neonatal #Jaundice
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
Inherited forms of Hyperbilirubinemia ... Decreased MRP2 - Conjugated ... Decreased OATP1B - Conjugated ... Inherited #forms #Hyperbilirubinemia ... hepatology #pediatrics #peds
Threshold for Initiating Exchange Transfusion by Risk Stratum. Bhutani et al. Pediatrics. 1999. #Peds #Pediatrics #Diagnosis #Management
#Peds #Pediatrics ... Management #Neonatal #Jaundice ... #Hyperbilirubinemia
Assess risk for developing subsequent neurotoxicity. This will tell you: a) phototherapy or b) exchange transfusion #Peds #Pediatrics
transfusion #Peds ... Management #Neonatal #Jaundice ... #Hyperbilirubinemia
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