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diagnosis differential causes hepatology management liver syndrome treatment hyperthyroidism acute ascites chronic gastroenterology hypocalcemia injury rheumatology biliary hypercalcemia lfts pediatrics
Clinical Examination for Liver and Biliary Diseases 1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Liver and Biliary Diseases ... erythema 2) Face: Jaundice ... Xanthelasma and jaundiced ... #physicalexam #cirrhosis ... #liver #disease
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... Infectious • Hepatitis ... Primary Biliary Cirrhosis ... Differential #Diagnosis #Algorithm
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... - Wilson disease ... Venoocclusive disease
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 Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... before the onset of jaundice ... metabolic liver disease ... (Wilson disease
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... discomfort Signs: Jaundice ... of autoimmune disease ... #Diagnosis #Algorithm
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
of Autoimmune Hepatitis ... - Onset of jaundice ... before the onset of jaundice ... metabolic liver disease ... (Wilson disease
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... SLE, autoimmune hepatitis ... ) - Autoimmune hepatitis ... Primary biliary cirrhosis ... (TTG) - Celiac disease
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Chronic liver disease ... (cirrhosis or chronic ... hepatitis) - 80% ... failure - 3-5% Cirrhosis ... HIV-related, Renal Disease
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... cholestasis → Cirrhosis ... hyperpigmentation • Jaundice ... but elevated as disease ... Diagnosis: • Viral hepatitis
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... hepatocyte damage (eg, hepatitis ... , hepatic cirrhosis ... drugs, biliary cirrhosis ... postoperative jaundice
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