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Jaundice Differential Diagnosis: A short guide

By Dr. Khudhur Mohammed @khudhur_moh

#jaundice #gastroenterology #algorithm #differential #diagnosis #hyperbilirubinemia #bilirubin
Jaundice Differential ... khudhur_moh #jaundice ... #gastroenterology ... #algorithm #differential
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... , hepatitis, hepatic ... postoperative jaundice ... neoplasms #Jaundice ... #unconjugated #differential
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
onset RUQ pain, jaundice ... Hepatobiliary #hepatology #hepatitis ... #differential #
Upper GI Bleed - Management Algorithm

Upper GI bleed Suspected: Melena, hematemesis, coffee-ground emesis, BRBPR
Initial Stabilization
Concern for
Consult GI ± EGD ... UGIB #GIBleed #Differential ... gastrointestinal #gastroenterology
Acute Esophageal Necrosis
History: Hematemesis and/or melena (70%), Dysphagia, Epigastric/chest pain, Sepsis
Diagnosis EGD and Biopsy
Differential: Melanosis, Melanoma,
Sepsis Diagnosis EGD ... and Biopsy Differential ... diagnosis #management #gastroenterology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Origin (FUO) - Differential ... Non-infectious hepatitis ... CMV • Viral hepatitis ... • Protozoa (eg ... #FUO #Chronic #Differential
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Regions - Frequent Differential ... - HIV, herpes, hepatitis ... B, hepatitis C ... plague, anthrax • Jaundice ... Returning #Traveler #differential
Causes of Nausea and Vomiting - Differential Diagnosis Framework

Chemoreceptor Trigger Zone/Area Postrema:
 • Drugs:
	- Chemo agents
	-
and Vomiting - Differential ... Pancreatitis • Hepatitis ... vomiting #emesis #differential ... diagnosis #causes #gastroenterology
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
autoimmune thyroiditis, hepatitis ... microscopic colitis Differential ... Diagnosis #Algorithm #gastroenterology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis