182 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... onset RUQ pain, jaundice ... crisis Acute Hepatic ... Liver transplant ... Hepatobiliary #hepatology #hepatitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... : <5 mg/dL • Hepatic ... imaging: Hepatic ... if severe • Hepatic ... hepatology #obstetrics #hepatitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... hyperpigmentation • Jaundice ... or higher • Liver ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Examination for Liver ... Flapping tremor (hepatic ... erythema 2) Face: Jaundice ... Xanthelasma and jaundiced ... Palpable gallbladder, Hepatic
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... NAFLD, Autoimmune hepatitis ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... Sepsis, Viral Hepatitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... (Drug-induced liver ... ) • Non-hepatic
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... before the onset of jaundice ... ) or metabolic liver ... Possible drug-induced liver
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... - Onset of jaundice ... before the onset of jaundice ... ) or metabolic liver ... Possible drug-induced liver
Right Upper Quadrant Pain
Liver:
 - Infectious: Acute viral hepatitis, Liver abscess
 - Non-infectious: hepatitis (Alcohol, Medications),
Quadrant Pain Liver ... Infectious: Acute viral hepatitis ... , Liver abscess ... Non-infectious: hepatitis ... Medications), Hepatic
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... load (i.e., pre-hepatic ... conjugation (i.e., hepatic ... excretion (i.e., post-hepatic ... Pediatrics #Neonatal #Jaundice