43 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PT (INR), Normal ... PTT, Normal PT ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Algorithm Pre-Hepatic ... Cholangitis #Jaundice ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... K Antagonists, Heparin ... to identify the cause ... ISNeducation #Abnormal ... #diagnosis #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... e.g. heparin ... Jcortesizaguirr #Abnormal ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Diagnosis for a Prolonged ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... amyloidosis #Abnormal ... #differential #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... imaging: Normal ... • Histology: Normal-mild ... imaging: Hepatic ... Disease #Pregnancy #hepatology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... of air in the hepatic ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... Normal Peritoneum ... Hepatic congestionl ... peritonitis #Ascites #Causes ... #differential #hepatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... hemoglobin/hemosiderin, Hepatic ... hemosiderin • PT/aPTT normal ... Differential #Diagnosis #Management ... #Algorithm #hematology