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Jaundice Differential Diagnosis: A short guide

By Dr. Khudhur Mohammed @khudhur_moh

#jaundice #gastroenterology #algorithm #differential #diagnosis #hyperbilirubinemia #bilirubin
Jaundice Differential ... khudhur_moh #jaundice ... #gastroenterology ... #algorithm #differential ... #diagnosis #hyperbilirubinemia
Algorithm and Differential Diagnosis of Hyperbilirubinemia 
Direct = Conjugated
Indirect = Unconjugated

#Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Algorithm and Differential ... Diagnosis of Hyperbilirubinemia ... #Diagnosis #Jaundice ... #Hyperbilirubinemia ... #Differential #
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Management #EM #IM #GI #Jaundice ... #Hyperbilirubinemia ... Workup #Evaluation #Differential
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... - Unconjugated Hyperbilirubinemia ... Hepatic - Conjugated Hyperbilirubinemia ... Cholangitis #Jaundice ... #Differential #
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... of pathologic hyperbilirubinemia ... Pediatrics #Neonatal #Jaundice ... #Algorithm #Differential
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
to Conjugated Hyperbilirubinemia ... - Differential ... #Conjugated #Hyperbilirubinemia ... direct #bilirubin #Differential ... Diagnosis #Algorithm #gastroenterology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
common hereditary hyperbilirubinemia ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... hepatology #diagnosis #gastroenterology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Unconjugated hyperbilirubinemia ... postoperative jaundice ... neoplasms #Jaundice ... #unconjugated #differential
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
onset RUQ pain, jaundice ... Supportive with treatment ... hepatology #hepatitis #differential
Prevention and Treatment of Nutritional Complications after Bariatric Surgery
Types of Bariatric Surgery:
 • Adjustable Gastric Banding
Prevention and Treatment ... Surgery #Diagnosis #Differential ... #Treatment #Complications ... #Deficiencies #Gastroenterology