18 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... , HIV, HTLVI, Hantavirus ... Prunelle Getten #AdultOnset ... diagnosis #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Systemic AOSD: high fever ... , CRP, AST+ALT, ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... disorder, Mycoplasma, HIV ... , EBV • Associated ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... ), EBV infection ... - Pel-Ebstein fever ... body, but can also ... #NonHodgkins #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... to repair DNA, as ... aplastic anemia Treatment ... Anemia #oncology #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Pathophysiology: 2 hit ... explain symptoms • Fever ... : 33% • Treatment ... : No • Treatment ... #diagnosis #comparison
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
• Presents as ... symptoms • >50,000 HIV ... Headache (45%) • Fever ... Epstein-Barr virus (EBV ... antibody test) Treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... • Symptoms: Fever ... • Symptoms: Fever ... symptoms such as ... effect/Edema • EBV
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Renal Failure Treatment ... • Steroids: IV ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
glomerulonephritis) • Anti-GBM ... Coronary arteries - Fever ... aneurysms can also ... Vasculitis: • Fevers ... differential #diagnosis #rheumatology