20 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
(TLS) and Treatment ... Abnormalities of TLS ... Laboratory TLS ... #TLS #diagnosis ... #management #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... only curative treatment ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... to repair DNA, as ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... MatthewHoMD #TLS ... #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... Generalized fatigue - ALS ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... permeability Diagnosis ... (for secondary APS ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as ... tests ↑ AST ↑ ALT ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... Differentiation #Syndrome ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... HIV, Influenza, TSS ... #Differential #Diagnosis ... #Management #causes