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diagnosis hematology management syndrome algorithm chronic classification differential mds myelodysplastic treatment aplastic cancer dehydrogenase dermatology disorders elevated erythematosus gammopathy hemeonc
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... - infiltrates (anemia ... • Age: 60-80 Clonal ... CLL Symptoms: • ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... cytometry → >500/uL clonal ... marrow failure with anemia ... uw_IMresidency #CLL ... #Leukemia #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... • Neutropenia, anemia ... ’s lymphoma or acute ... leukemia #CLL ... #workup #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Script Signs and symptoms ... Consider stem cell ... progress to MDS or acute ... leukemia • Associated
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Allogeneic stem cell ... treatment #hematology #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... common - T Cell ... ~10% - B-Cell ... Treated Like Acute ... Leukemias, very
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral ... Labs: • CD4+ T-cell ... • Leukocyte-lymphocyte ... enzymes ↑ • Mild anemia ... Photophobia • Lymphocytic
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
• Hemolytic Anemias ... Injury: • Early acute ... hepatitis • Acute ... Lymphomas • Leukemias ... associated with any symptoms
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... count (anemia) ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... diagnosis #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Episcleritis Signs and Symptoms ... general feeling of ill ... development of skin symptoms ... #dermatology #oncology
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