459 results
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Pathogenesis and Joint ... poly-articular joint ... Joint involvement ... space decr joint ... RheumatoidArthritis #RA #pathophysiology
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
together) • Joint ... closer to the joints ... ) • Joint Subluxations ... (Joint deformities ... Radiology #Clinical #Pathophysiology
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Inflammation of joints ... commonly large joints ... Oligoarthritis: Joint ... pain in a few joints ... ReactiveArthritis #pathophysiology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
and Degenerative joint ... Inflammatory Joint ... Swelling stimulates joint ... • Moving the joint ... JointPain #Diagnosis #pathophysiology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Stimulation of joint ... loading / use of joint ... Disruption of normal joint ... movement of the joint ... Osteoarthritis #OA #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Excessive urination, Abdominal ... weakness, Bone/joint ... Secondary #Tertiary #pathophysiology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
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easily leaks into joints ... in a peripheral joint ... Neutrophils enter joint ... degradative enzymes into joint ... Hyperuricemia #Pathophysiology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
involving small joints ... inflammatory) • joint ... • synovitis; joint ... tenderness • joint ... narrowing) • Ultrasound
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
patellofemoral joint ... patellofemoral joint ... patellofemoral joint ... Patellofemoral #Syndrome #pathophysiology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
crystals from joints ... high-resolution ultrasound ... warm, swollen joint ... sclerosis & cysts, joint ... Signs #Symptoms #Pathophysiology