31 results
Paget's Disease of Bone

 • Characterized by an ↑ rate of bone turnover with both excessive
by an ↑ rate of bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones ... #management #treatment
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long bones ... BrighamChiefs #Bone ... #differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... stimulation (placenta/Bone ... - Highest • Bone ... Intestine - Other causes ... - Bone symptoms
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Hypercalcemia - Differential ... Diagnosis Algorithm ... Granulomatous Disease ... Miscellaneous - Bone ... #causes #endocrinology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Fragility Fractures - Differential ... Diagnosis Algorithm ... Tumours - See Bone ... • Bone Marrow ... #Orthopedics #Causes
Hypocalcemia - Diagnosis and Management
PTH Independent (↑ PTH)
 • LOW VIT D
    -
, Kidney Disease ... - Accelerated Bone ... Formation: Hungy Bone ... endocrinology #differential ... #algorithm
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
inflammatory disorder of bone ... inflammation of the bones ... Rule out other causes ... osteoarticular and skin disease ... Rheumatology #diagnosis #management
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Diagnosis Algorithm ... • Meniere's Disease ... Media • Temporal Bone ... #Causes
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Diagnosis Algorithm ... Chemotherapy • Bone ... Celiac, IBD) • ... endocrinology #causes
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Diagnosis Algorithm ... Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... #Orthopedics #Causes